feed-back inhibition (end product inhibition)

feed-back inhibition (end product inhibition)
A metabolic control mechanism in which the end product of a biochemical sequence is able to inhibit the activity of an early enzyme in the sequence, thereby controlling the metabolic flux through this
pathway. As an example, isoleucine controls its own synthesis by inhibiting threonine deaminase; adenosine 5-triphosphate (ATP) and citrate control glycolysis by inhibiting phosphofructokinase.

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